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Nature 569 , 723728 (2019)

[DOI] [PubMed] [Google Scholar] 50.Hibuse T, Maeda N, Funahashi T, Yamamoto K, Nagasawa A, et al

Why it matters: Short telomeres are associated with cellular senescence (aging) and disease

Less frequent symptoms associated with injection site reactions may include fever, intense pain, injection site blistering, and firmness under the skin, which could signify a more serious reaction requiring medical attention

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The glutamate produced during the glutamine metabolism is further converted into -ketoglutarate (-KG) through glutamate dehydrogenase 1 (GLUD1), transaminases such as glutamate-oxaloacetate transaminase (GOT), glutamate-pyruvate transaminase (GPT), and phosphoserine transaminase (PSAT) and subsequently participates in the TCA cycle