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At higher doses, some individuals, particularly those predisposed to prolactin sensitivity, may experience symptoms including mood changes, sexual dysfunction, and in rare cases, mild gynecomastia

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doi: 10.1186/s13287-025-04352-z

The studies began with the determination of the optimal dosing for Cagrilintide in both chow-fed and high-fat diet (HFD)-fed wild-type (WT) mice, followed by analyses of its receptor dependence using receptor activity-modifying protein (RAMP) knockout (KO) models, and mechanistic studies involving neuronal activation and gene expression profiling [2]

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