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While they may not replace hormone replacement therapy entirely, they can complement it effectively

When deficient, it can increase the accumulation of homocysteine, which is significant in the development of cerebrovascular diseases and cognitive impairment (58)

Interestingly, interventions that boost NAD + levels resulted in extended lifespan in worms and mice 108,109,111,247 , suggesting a therapeutic potential for raising NAD + in various pathological conditions or age-associated diseases

Effects of Chuanhuang Decoction on renal function and oxidative stress in patients of chronic kidney disease at stage 2-4 complicated with acute kidney injury

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ANCOVA was used to compare mean levels of bone specific alkaline phosphatase (BAP) and tartrate-resistant acid phosphatase (TRAP 5b) in PPI users versus non-PPI users after controlling for age, sex, body mass index, timed up an go test, 25(OH)D, estimated glomerular filtration rate, parathyroid hormone, smoking, daily dairy intake, alcohol consumption, type 2 diabetes mellitus, current or past steroid exposure, and loop and thiazide diuretics