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Resolving these issues and apparent contradictions may lead to development of novel alternative therapeutic approaches targeting common lipid pathways shared by various neurodegenerative diseases

Ultrastructural lesions and immunohistochemical analysis of Bcl-2 protein expression in the kidney of chickens with experimental ochratoxicosis

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doi: 10.1002/jcp.24217

R., Bonomini, M., & Arduini, A

It was demonstrated that global targeting of mTOR caused both anti-survival and pro-survival mitochondrial response, which were differentially exhibited in diverse cancer cells according to their intrinsic sensitivity to mTOR inhibition and hyperactive PI3K/AKT/mTOR activity status and/or growth factor-dependence (112)