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Cell 1 : 543551 Rueffli AA, Smyth MJ and Johnstone RW (2000) HMBA induces activation of caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistance

Some mild nausea may occur, particularly in the first week of each dose increase

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Shorey et al., 2013, observed increased morbidity and no reduction in lung tumorigenesis in offspring born to mothers receiving transplacental and lactational exposure to the carcinogen dibenzo[def,p]chrysene and supplemented with dietary sulforaphane (400 ppm) in contrast to many reports of chemoprotection in adult animal models [124]