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Another pivotal endocrine abnormality involves altered gonadotropin secretion, particularly an increased luteinizing hormone (LH) to follicle-stimulating hormone (FSH) ratio

J.KalyanaramanB.et al (2011)

Other health issues are also common among many individuals with very low levels of Vitamin B12

Clinicians and other ancillary health workers should be properly trained to have a high index of suspicion of thiamine deficiency in situations of unbalanced nutrition that has lasted for 2 to 3 weeks to avoid misdiagnosis of the life threatening WE or irreversible brain damage caused by KS

Pale brown to black lentigines are the most common feature and are present in 70% to 80% of affected individuals

npj Antimicrob Resist 3 , 53 (2025)