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Low Ceruloplasmin levels may also be found in Menkes disease, malignancy, inflammatory bowel disease, thyroid disease, neonates, heterozygotes for WD and aceruloplasminemia Methods: Electronic medical record review Results: A 12-year-old Hispanic nonverbal autistic male with history of constipation and urticaria pigmentosa was referred for elevated serum transaminases with normal bilirubin levels

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doi: 10.3389/fbioe.2025.1668524 Received 18 July 2025 Revised 04 November 2025 Accepted 13 November 2025 Published 05 January 2026 Volume 13 - 2025 Edited by George Alexander Truskey, Duke University, United States Reviewed by Wagner Moneda Telini, Centro Universitrio de Votuporanga, Brazil Mai Abusalah, al-Ahliyya Amman University, Amman, Jordan, Jordan Updates Copyright 2026 Xiao, Li, Mu, Sun, Wang, Chen, Ma, Cao, Yang, Shao, Ding, Cui and Du

This may be due to the fact that lower birth weight is associated with a later higher ratio of fat mass to fat-free mass and more abdominal adipose tissue [113]

Table 1: With regard to the metabolome across the spectrum of neurodegeneration, citicoline may crosstalk with glucose metabolism and may protect neurons from hyperglycemic conditions (Gao et al., 2017