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7.2 Personalized antioxidant strategies: One size does not fit all As the understanding of oxidative stress deepens, it is clear that uniform supplementation strategies may be insufficient

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Complex mixtures of polyphenols found in foods like wine, tea, and fruits exhibit synergistic effects, also providing potent antioxidant and anti-inflammatory properties

Importantly, overexpression of the wild-type (WT) AMPK1 catalytic subunit in shGDH1 cells not only increased cytosolic NADPH level and alleviated disulfide stress (Fig