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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Basile D.P., Leonard E.C., Beal A.G., Schleuter D., Friedrich J

de Jong K, Rettig MP, Low PS, Kuypers FA

3.2.11 Diketone derivant: Curcumin Curcumin ( 17 ) is a kind of diketone compound extracted from turmeric, which has anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenesis, anti-bacterial, anti-viral, anti-fibrotic, anti-depressant, anti-ischemic, immunomodulatory, and neuroprotective properties

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-Amino--carboxymuconate--semialdehyde decarboxylase (ACMSD) inhibitors ACMSD plays a crucial role in the kynurenine pathway, serving as a branching point between NAD + and acetyl-CoA production 234