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however, commercially viable product titres have not yet been reached, partly due to issues arising from the late steps of the biosynthetic pathway 6,7

To better understand events that occur during CRC formation and as part of the Human Tumor Atlas Network (HTAN) 7 , we performed transcriptome, proteome, metabolome and lipidome analyses of n = 93 samples from six persons with FAP (528 per person) representing different stages of cancer progression: unaffected colonic mucosa, benign polyps and dysplastic polyps