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After euthanizing the mice on day 12, periwound skin tissue was collected from different groups for follow-up experiments, as detailed in the subsequent section

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doi: 10.1248/jhs.57.215

Iron overload in bone marrow-derived macrophages can upregulate SLC7A11 expression via the ROS-NRF2-antioxidant response element (ARE) axis to reduce cellular sensitivity to ferroptosis [112]