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In Japan, the intravenous formulation Stronger Neo-Minophagen C (SNMC) has been approved for chronic hepatitis for over 4 decades, with long-term studies demonstrating its efficacy in reducing ALT levels and preventing hepatocellular carcinoma (Kumada, 2002

This melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from oxidation of already-existing melanin

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PMID: 10201372

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[DOI] [PubMed] [Google Scholar] 62.Alves AC, de Carvalho PT, Parente M, Xavier M, Frigo L, Aimbire F, et al