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Inhibiting nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy, a type of selective autophagy for the degradation of ferritin by lysosomes, increases iron storage and limits ferroptosis in cancer cells 48,49 (Fig

Thus, interference with GSH synthesis in FoB induced an increase in mitochondrial mass without concomitant mtDNA replication

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Although the protection against necrosis was still present at 24 h, there was clear evidence of a limited number of apoptotic cells and caspase activation [58]