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Specifically, RES reduced the levels of inflammatory factors, including TNF-, IL-1, and interferon-gamma (IFN-), and decreased the expression of the proteins Bax and caspase-3 through the mitochondrial-dependent apoptotic pathway ( Polyphenols exhibit enhanced efficacy in scavenging radiation-induced free radicals, particularly the hydroxyl radical, and in inhibiting lipid peroxidation, which can be attributed to their abundant phenolic hydroxyl groups

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One week after AAV-shM1 or AAV-NC (510 11 GC/mouse) injection, FA (0.1 mg/kg/day) was administrated along with Ang II for 4 weeks (Fig