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HS exhibits a biphasic effect in cancer biology: at low concentrations, it enhances mitochondrial function and promotes glycolysis, thereby supporting cancer cell proliferation, whereas at high concentrations, it inhibits proliferation

Because metabolite-receptor interactions are often highly stereospecific 53,54 , we developed a synthesis employing Sharpless chiral resolution and subsequent chirality transfer via Claisen rearrangement to access the two enantiomers of bemeth#1, (3 R) -bemeth#1 and (3 S) -bemeth#1 (Fig

James J DiNicolantonio, Carl J Lavie, Hassan Fares, Arthur R Menezes, James H O'Keefe, 2013 Apr 15 - The Effect of L-Carnitine on Critical Illnesses Such as Traumatic Brain Injury (TBI), Acute Kidney Injury (AKI), and Hyperammonemia (HA)