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Public Health 8 (5), 14021419

These in vitro findings were corroborated by clinical observations, where subjects treated with DEC-containing serum exhibited significant improvements in skin lightness and reduced yellowness, with a high participant satisfaction rate of 97%

Its unique properties, dissimilar to other IgGs, are the lack of influence on the classical complement component pathway and, through a property called fab-arm exchange (FAE), inhibition of the formation of large immune complexes ( These specific qualities of IgG4 are related to its varied affinity to specific Fc gamma receptors (FcRs)

[106], the authors studied the effect of CSE exposure on VEGF release by human lung fibroblasts demonstrating that the TGF- receptor/mothers against decapentaplegic homolog 3 (Smad3) pathway mediates CSE-induced VEGF production

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CNS Drugs 25 (7), 597606