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Notably, LBP could counteract these processes by suppressing ROS and MDA levels, enhancing antioxidant enzymes [e.g., SOD, CAT, GSH-Px, glutathione transferase (GST), and GR], and decreasing proinflammatory cytokines [e.g., IL-1, IL-2, IL-6, IL-8, TNF- , interferon (IFN-), MCP-1, intercellular adhesion molecule-1 (ICAM-1) and serum amyloid A3 (SAA3)] in the DN (63, 72, 73, 7779)

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5f) and elicited remarkable cell death under glucose starvation (Extended Data Fig

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