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Furthermore, it has the capacity to upregulate the activity of pivotal antioxidant enzymes, including superoxide dismutase (SOD), catalase, and glutathione peroxidase, which in turn protects cells from oxidative harm ( Coptis chinensis and its active metabolite berberine, through their dual effects of antioxidant stress and anti-neuroinflammation, constitute a potential intervention strategy for cerebral microcirculation disorders and BBB protection in hypoxic environments at high altitudes

When B12 is deficient, myelin begins to break down, exposing nerves to damage

R., Kim, D

Front Genet 11:562316

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Recent studies identified a novel copper-dependent form of cell death called cuproptosis, which is distinct from all other known pathways underlying cell death