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Kang B-J, Kim H, Lee SK, et al

Interestingly, while (R)-crizotinib, the clinically used form, is inactive against MTH1, the (S)-enantiomer of crizotinib selectively inhibits MTH1 catalytic activity

Nanoenzymes that are said to be functionalized, could be used for controlling and repairing/regenerative, at a molecular level, prion, amyloid protein misfolding with limited clearance, cytokines release inhibitors or enhancers, enzymes activators or depressors, antibodies, signaling molecules, RNA, enhancer or repressor factors, stem cells, as a challenge

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Desalting was carried out with stage tips with C18 extraction discs (Empore TM high performance extraction discs, 47 mm, 3 M Bioanalytical Technologies #2215)