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No standardized human dosing exists, and individual responses vary considerably

The one human trial that will measure tolerability directly has not started reporting it is only recruiting (planned 2026), studies a topical gel on small standardized wounds , and lists safety as a secondary, not primary, outcome (NCT07437586)

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Since melatonin helps regulate the sleep-wake cycle, this may explain why Epitalon is often discussed for sleep quality and restorative health

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