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However, this level may decrease during physical stress or illness

In rheumatoid arthritis -associated interstitial lung disease, elevated PAD2 expression in lung fibroblasts promoted a pro-fibrotic phenotype, while overexpression of syndecan-2 (SDC2) inhibited PAD2 and protected against BLM-induced fibrosis [94]

Weight gain that occurs early (before 20-24 weeks) seems to be crucial

2023 Lee et al

Cell Factories 2023, 22, 224

Evaluation of fat mass and lean mass using Echo-MRI and X-ray CT system Consistent with the significant increase in body weight, vehicle-treated MC4R KO mice showed a significant increase in fat and lean masses