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The thiol-binding metals are not only those best-known for their thiol-binding ability, such as Mercury(II), Cadmium(II), Lead(II), Zinc(II), Arsenic(III and V), but also many more, such as Copper(I), Chromium(VI to III), Silver(I), Gold(I and III), Ni(II and III), Co(I and III), Al(III)

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Additionally, DAPA reversed the altered expression of ferroptosis-related genes at both the mRNA and protein levels: The decreased expression of GPX4, SLC7A11 and FTH-1 in renal tissues of the si-Nrf2 group was improved by DAPA, while the elevated expression of TFR-1 was inhibited by DAPA (Fig

10.4161/pri.5.3.16893 11 AtarodD.MamashliF.GhasemiA.Moosavi-MovahediF.PirhaghiM.NedaeiH.et al (2022)