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Persistent mineral limitations activate complex signaling networks involving phytohormones, reactive oxygen species (ROS), Ca 2 fluxes, and transcriptional reprogramming, which integrate with tolerance pathways to drought, salinity, and temperature extremes (Fig

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et al., 2022), and both of these two phyla were also reduced in the EpCAM +/ mice compared to WT mice (Figures 5E,F)

535,536 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an essential regulator of LDL-C metabolism