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Description

To determine ROS production, cells were incubated with DCFH-DA (10 M) for 30 min, washed twice with cold PBS

& Mansel, R

This results in increased hydrolysis of glutathione with resultant low serum levels

As OxS plays an important role in PSC activation and fibrosis, the use of antioxidants to inhibit OxS is valued by researchers [36, 37]

Excessive sugar intake exacerbates insulin resistance and low-grade inflammation, while a high-fat diet amplifies oxidative stress and adipose tissue inflammation (24)