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Antibiotic-induced biofilm formations in pseudomonas aeruginosa strains kpw.1-s1 and hrw.1-s3 are associated with increased production of eDNA and exoproteins, increased ROS generation, and increased cell surface hydrophobicity

It results from a combination of increased sebum production by sebaceous glands and hyperkeratinization, with a known role for transcription factor GATA6 deregulation in its pathogenesis [33]

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Aging is also linked to the elevation of inflammatory cell (monocytes and neutrophil) counts and C-reactive protein (CRP) levels (Tang et al., 2017)

W., Wang D., Li X

Superoxide (O 2 ) is produced by one electron reduction of oxygen by different oxidases including dihydro nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, xanthine oxidase, cycloxygenase as well as by the mitochondrial electron transport chain during the course of normal oxidative phosphorylation which is essential for generating ATP (Evans et al ., 2003) (Fig