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After washing with cold PBS, the cellular uptake of NP4 was measured via CLSM

A.XieJ.Ganapathy-KanniappanS.GriffithJ.LiuA.McDonaldC.et al

doi: 10.1152/ajpgi.1999.276.3.G639 18

The peptide works exclusively through peripheral mechanisms in adipose (fat) tissue rather than through central nervous system pathways that regulate appetite and feeding behavior