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Liu C, Yan X, Zhang Y, et al

Current challenges include the absence of specific biomarkers and targeted inhibitors, necessitating preclinical validation of disulfidptosis-inducing agents to advance precision oncology strategies for SLC7A11-driven malignancies (Figure 7) (Table 3)

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This connection could be possibly through the mTORC1 signaling pathway which is implicated in the process of cancer development where in LeuRS acts as a regulator of mTORC1 signaling [90, 91]