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To identify proteins with significant differences, proteins satisfying all of the following conditions were defined as significantly changed proteins

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Briefly, folates that enter the liver have three potential destinations [2]: Folates can be converted into polyglutamate storage forms, or They can be secreted into the bile at the hepatic canalicular membrane mediated by MRP2/BRCP, whereby they return to the duodenum and jejunum and are subsequently reabsorbed, thus complete the cycle of enterohepatic circulation, or Folate monoglutamates, formed by hydrolysis of polyglutamate forms stored in hepatocytes, or delivered directly from the , can enter the hepatic portal vein , ultimately reaching the hepatic vein whereby they accumulate in and meet the one carbon requirements of, systemic circulation

Recent Progress in Doxorubicin-Induced Cardiotoxicity and Protective Potential of Natural Products

These results are consistent with the present study