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Silhavy et al., 2010

Atypical features of a Ure2p glutathione transferase from Phanerochaete chrysosporium

Development of multi-drug resistance has led doctors to look for milder prophylactic therapies in order to minimize the high cost of therapies (181)

In contrast, IRP2 knockdown or treatment with the ferroptosis inhibitor Fer-1 alleviates PC-12 cell damage by downregulating p53 levels and activating the SLC7A11-ALOX12 signaling pathway (Yao et al., 2024)

Clinical trials of the combination of dextromethorphan and quinidine, which affect the demethylation of the P450 cytochrome enzyme, have revealed improvement in the pseudobulbar effect in patients with ALS [256]