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All results from the literature refer to cytotoxic activities in different tumor cell lines (A549, MCF-7, SKOV3, PC-3, HepG2, U937) but not to animal experiments or human studies (Chang et al., 2015)

The pan-caspase inhibitor zVADfmk, partially blocked the induction of apoptosis at 48 h, and was ineffective after 72 h

If the treatment had continued to 72 weeks, the gap could have narrowed substantially

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It is specifically characterized by inflammation, demyelination, and neuronal loss and manifests with a range of neurological symptoms including numbness, tingling, vision impairment, cognitive impairment, and bladder and bowel dysfunction (Tafti et al., 2024)