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Likewise, given during reperfusion after clamping the common carotid arteries, BPC 157 reduced stroke (i.e., both early and delayed hippocampal neural damage, achieving full functional recovery in the Morris water maze test, inclined beam-walking test, and lateral push test) (Vukojevic et al., 2020) or reduced L-NAME-induced retinal ischemia in rats (Zlatar et al., 2021)

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Bufotalin (BT), a novel GPX4 inhibitor, increases the degradation of GPX4 and intracellular Fe 2+ level, causing ferroptosis in non-small cell lung cancer cells (Zhang et al

In vivo protection studies on mice The protective efficacy of each mAb was assessed using an IFNAR1-KO mouse model

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