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The last thing we want to see is someone who has struggled with weight loss and it was because of underlying thyroid disease that went undiagnosed because no one bothered to check a simple lab test

While the hyperinsulinemic-euglycaemic clamp performed during the PRESERVE study was not combined with a glucose tracer infusion, as the insulin infusion rate was the same as in Abdul-Ghanis original paper (40 mU/min/m 2 ) 19 we assumed this is sufficient to fully suppress endogenous glucose production

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