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This research may shed light on previous data identifying liver-derived IGF-I as one of the main factors in regulating the clearance of brain amyloid- (A) levels[68] and its potential implications in Alzheimers Disease (what will be further discussed in III.4.3.)

First, we demonstrated potent inhibition of secretion of gonadotropin, a sex steroid in mice, rats, men, and women by LH-RH antagonists Ac-d-Nal(2)1, d-Phe(4Cl)2, d-Pal(3)3, d-Cit6, d-Ala10-LH-RH (SB-75, cetrorelix) 39

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This component substantially affects muscular growth and fat metabolism

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