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Moreover, fluxes through 3-hydroxyisobutyryl-CoA hydrolase (3HBCOAHLm) and L-threonine 3-dehydrogenase (THDm) were increased, further supplying more acetyl-CoA via valine and threonine catabolism

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L.HardelandR.BhrM.et al (2002)

Am Ind Hyg Assoc J 1996, 57 (3), 279-84

One-third of the participants experienced a stable complete response as a result of using cobimetinib and vemurafenib in combination, which has a significant influence on long-term survival [291]