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Of note, phosphorylation levels of ERK1/2 (p-ERK1/2) and PKC (p-PKC) were equal between WT and XKR8 KO BMNs, indicating that these upstream signaling pathways remain intact in the absence of XKR8 (Extended Data Fig

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doi: 10.3390/metabo5040733, 54

This suggests that the quinone head group is a structural requirement for the anti-ferroptotic function

Furthermore, -hydroxybutyrylation was identified on histones, offering a new type of chromatin regulation as well 79

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