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(2024) A review of therapies for hyperpigmentation modulating the synthesis of eumelanin to pheomelanin, Archives of Dermatological Research, [online]

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NRF2 is reported to have suppressive effects on the lipogenic pathway via inhibiting the activity of LXR 64,70 , a transcription factor that supports lipid synthesis

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10.1007/s10517-009-0342-4 [DOI] [PubMed] [Google Scholar] Khavinson VK, Kormilets DY, Maryanovich AT (2017) Peptides (epigenetic regulators) in the structure of rodents with a long and short lifespan

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Due to the strong affinity of hyaluronic acid (HA) for the CD44 receptor, MDA-MB-231Br (a kind of metastatic breast cancer cell) may take up an ultra-small (~5 kDa) HA-PTX nanoconjugate through CD44 receptor-mediated endocytosis (142)

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