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Wu et al., describe a phospho-switch in which AMPK, when it is active due to pharmacological interference or general energy stress, phosphorylates and stabilizes TET2, the enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC)

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These data provide evidence for the feasibility, preliminary efficacy, and side-effect profile of CD19 CAR T-cell therapy in patients with severe autoimmune disease, Mller and colleagues wrote

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Insights into deglutathionylation reactions