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doi: 10.1002/IID3.48 228 JolliffeDAGreenbergLHooperRLGriffithsCJCamargoCAKerleyCPet al

Cationic systems like polyplex systems can escape from the endosomes/lysosomes because they have the ability to buffer pH and cause osmotic swelling of these organelles according to the so-called "proton sponge-mediated escape" theory

& Gendelman, H

In the treatment of IBD, therapeutic peptides are predominantly small molecules, typically comprising 210 amino acids, with 38 residues being most commona length that likely facilitates intestinal transport via peptide transporters while minimizing enzymatic degradation

The strains expressing the transporters had a higher resistance to Azoles compared to the parent strain

Fibroblast The survival controls for ARDS fibroblasts differ from those for healthy lung fibroblasts