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19B, when the concentration of MCNs/Ln/GD/FR NPs exceeded 200 g mL 1 , the survival rates of the four types of cells remained above 80%

Drug Metab Dispos, 32: 1383, 2004 Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 AcylGlucuronides are Unstable and Reactive Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 AcylGlucuronides are Unstable and Reactive Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 Are AcylGlucuronides Really Toxic

Compare this to peptides like GHK-Cu or TB-500 , which may require more frequent dosing due to shorter half-lives

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Viability assays with propidium iodide (PI) staining revealed a progressive increase in cell death, which was particularly pronounced 8 h post-treatment (Supplementary Fig

doi:10.1042/BJ20100208 Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, Yeh M, McCullough AJ, Sanyal AJ (2005) Nonalcoholic Steatohepatitis Clinical Research Network