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The protein encoded by ACSF2 is partially characterized as mitochondrial acyl-CoA synthetase, which catalyzes the formation of fatty acyl-CoA from ATP, CoA, and medium-chain fatty acids

H.IranshahiM.et al (2020)

Even though many women with lipedema also have obesity, the authors assert this cutoff value allows for a separation of lipedema of the legs from women without lipedema regardless of obesity

After deeply anesthetized via intraperitoneal injection of Zoletil (40 mg/kg) and Xylazine (10 mg/kg), the animals were perfused transcardially with 0.9% saline followed by 300 mL of 4% paraformaldehyde in 0.1 M phosphate buffer (PB), pH 7.4

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mBio 6 , e0176501715 (2015)