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We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)

Methylmalonic acid (MMA) is a blood test that seems to be a better measure of vitamin B12 deficiency than serum vitamin B12 level

If it were a breakthrough fat-loss drug, it would likely still be in aggressive pharmaceutical development

For this reason, the NIH has not established a tolerable upper intake level for B12

Patients who took a high dose of tirzepatide lost 22.5% of their body weight on average, or 52 pounds, better than any medication currently on the market

When both mechanisms operate simultaneously, you create a metabolic state where the body is consuming fewer calories while simultaneously breaking down fat reserves faster