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[195] [212] This internalization is mediated by RhoA activation and its downstream effector ROCK, a process that is TAAR1-dependent

Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt

Our results also indicated ALC was a safe agent without additional adverse effect compared with placebo

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Ammonia directly inhibits critical TCA cycle enzymes, including KGDH, isocitrate dehydrogenase, and malate dehydrogenase, compromising oxidative phosphorylation (OXPHOS) (Prasad et al

This review aims to serve as a comprehensive reference for clinical and laboratory findings for those who are confronted with pediatric and adult patients with a possible diagnosis of a mitochondrial lcFAOD