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Accordingly, diverse BTKi are currently under study for both RRMS and PPMS in ongoing clinical trials, the most advanced ones being evobrutinib and tolebrutinib (184)

2020Nov

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doi: 10.1007/s00018-019-03331-x 45 WinslowSOdqvistLDiverSRiiseRAbdillahiSWingrenCet al

Graner et al showed that the isopeptidase USP2a (ubiquitin-specific protease-2a) interacts with and stabilises FASN protein in prostate cancer (Graner et al, 2004)