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When corneal wounds re-epithelialize, the migration and proliferation of epithelial cells work in tandem, despite the fact that they operate independently [283]

The sensitivity of the spin-trapping technique is negatively affected by the dismutation of -H spin-adducts to nitrones and hydroxylamines 8,11 , whereas analyses in biological matrices are further complicated by the propensity of nitroxides to undergo one-electron reduction or oxidation either to EPR-silent hydroxylamines or to oxoammonium salts 12,13,14

Inhibition of COX-2 by NSAIDs blocks PG production at sites of inflammation, whereas inhibition of COX-1 in other tissues (platelets and the gastroduodenal mucosa) leads to common adverse effects of NSAIDs, such as bleeding and gastrointestinal ulceration ( Owing to the adverse effects of NSAIDs and corticosteroids, disease-modifying antirheumatic drugs (DMARDs), a class of immunosuppressive and immunomodulatory agents, are developed to prevent and relieve RA aggression

Catalase activity increases for hydrogen peroxide breakdown, and total glutathione levels rise, creating stronger hydroxyl radical quenching capacity than glutathione alone

To ensure data quality, any cells exhibiting a change in series resistance (Rs) exceeding 20% during the recording were excluded from the analysis

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