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J Oncol 2019;2019:5956867

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& Dinarello, C

Li Y, Chu F, Li P, Johnson N, Li T, Wang Y

The 2025 review by Sychowski and Cierniak in International Journal of Molecular Sciences the most recent comprehensive overview states explicitly that the mechanism of action remains unclear and that information on short- and long-term toxicity, genotoxicity, and carcinogenic potential is missing from the analysed literature, and would be required before any approval as an active pharmaceutical ingredient

Grosse 2 1 ETH Zurich, Zurich, Switzerland, 2 Universittsspital Basel, Basel, Switzerland, 3 Medizinische Hochschule Hannover, Hannover, Germany, 4 Institute of Biomedicine of Seville, Seville, Spain Background and Aims: Stroke survivors face a high risk of recurrence, with 23% of all strokes being recurrent