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However, any combination approach should be undertaken with medical supervision and careful monitoring of cumulative effects

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They could have side effects or potential for overuse, leading to medication-overuse headaches

This requires them to truly understand that metabolic state determines the bactericidal efficiency of antibiotics, nutritional metabolites are more beneficial than inhibitors for human beings, and increasing the uptake of antibiotics is preferable to the inhibition of drug enzymatic hydrolysis

Nagrao MV, Skoulidis F, Montesion M, Schulze K, Bara I, Shen V, HuS, Elamin YY, Le X, Goldberg ME, Wu CJ, Zhang J, Barreto DS, Rinsurongkawong W, Simon G, Roth J, Swisher SG , Lee JJ, Tsao A, Papadimitrakopoulou V Gibbons DL, Glisson BS, Va M, Alexander BM, Frampton GM, Albacker LA, Shames DS, Zhang J, Heymach JV