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doi: 10.1038/s41589-019-0408-1 23 KuhnHBanthiyaSvan LeyenK

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Phase II is conjugation: cytoplasmic enzymes conjugate the functional groups introduced in the first phase reactions, most often by glucuronidation or sulfation, and also acetylation and methylation

Enrichment shows an 8.7-fold increase in RT-deletion for the G4 HIV-1 LTR and a significant increase in RT-deletion for the target G4 sequence (Supplementary Fig