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At physiologic pH (such as in serum and joint tissues), uric acid (which is a weak acid) exists as the anion urate, and plasma protein binding is quite low for urate

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They achieve this by partially disrupting the balance of certain chemicals in cells to eliminate tumor cells and reverse resistance

doi: 10.3389/fimmu.2023.1187890 194 WuM.-Y.LuJ.-H

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