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Such findings, together with the growing awareness of the importance of Se to general health, require further work primarily on creating an acceptable range of blood Se concentration or other measures to determine optimal Se consumption and, consequently, to guarantee adequate Se supplementation in populations at high risk of low Se intake

Expression of the glutamine transporter Slc1a5 is regulated by MYC and is elevated in MYCdriven liver tumors 11, 12

When excessive ROS production exceeds the effective capacity of cellular antioxidants, oxidative stress occurs, disrupting redox homeostasis and impairing cellular components such as proteins, DNA, RNA, and lipids

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According to the results of our investigation, silymarin treatment significantly reduced AST and ALT levels, indicating a pattern of reduced liver necrosis before patients crossed the line of liver cirrhosis