The most commonly reported side effects include: Pain, bruising, or redness at the injection site Mild nausea or stomach upset Diarrhea Headache Allergic reaction (rare) Because MIC injections are compounded formulations, the quality and composition can differ from one clinic to another
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If deficiency is confirmed, treatment is typically clinician-supervised and intramuscular
The vitamin is more quickly absorbed when administered in injection format, but this is also what makes it so effective for weight loss
The standard regimen involves: Loading doses without neurological involvement : 1 mg intramuscularly three times a week for 2 weeks [3] [8] Loading doses with neurological involvement : 1 mg intramuscularly on alternate days until no further improvement [3] [8] Maintenance therapy : 1 mg every 23 months for life in cases of pernicious anaemia or irreversible malabsorption (every 2 months if neurological involvement) [3] [8] This aggressive approach aims to prevent irreversible neurological damage, though recovery of established neuropathy may be incomplete, particularly if treatment is delayed
This analysis excluded trials in those with end-stage renal disease, who are at high risk of cardiovascular events and mortality